An advanced machine learning approach to increase diagnostic accuracy in
atypical Alzheimer's disease cases 
   Lead Investigator:    Erica Cruz
   Institution      :    Old Dominion University
   E-Mail           :    ecruz009@odu.edu
   Proposal ID      :    1564



   Proposal Description:
   Aim 1: To discover volumetric MRI imaging biomarkers for dementia by studying  feature-based multiresolution-fractal texture extraction, Kullback-Leiber         Divergence (KLD) multiclass feature selection, and fusion with feature-less       deep ML methods.                                                                 Aim 2: To combine advanced regression based feature fusion and prediction for     MRI biomarkers and neuropsychological information, informant history, AD risk     factors, and functional status for accurate and hard-to-detect AD                 classification.